Grand Medical Group

About us

Grand Medical Group AG is a group of pharmaceutical companies specialized in the development, production, registration and introduction into medical practice of modern innovative products based on organic, synthetic and herbal compounds.

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10 Kornmarkt Street, CH - 6004 Luzern, Switzerland

+41 415880810



Black Cohosh  (Cimifuga racemosa rhizoma) extract standardized to contain 2.5% of triterpene glycosides 
Soy (Glycine max L.) extract complex standardized genistein, daidzein, and glycitein
Horny goat weed (Epimedium) extract containing 60% of icariin
Lin seed (Linum usitatissimum) standardized extract
St. John's Wort (Hypericum perforatum L. herbae) extract, standardized to contain 0.3% of hypericin


MENOLYTIN ADVANCE is recommended as a health supplement to diet, which helps to improve mental and somatic feeling of women with menopause (reduces breast pain and breast tenderness, prevents of night sweats and hot ?ashes, headache) due to providing of estrogen substitution, and anti-in?ammatory e?ects; eliminates anxiety, irritability, and mood swings, prevents depression, sleep disturbance and mood disorder development. Also, MENOLYTIN ADVANCE in complex therapy helps to manage osteoporosis development in women who are in or after menopause and prevent the development of atherosclerosis. 

During woman's post-menopausal period in life, the production of estrogen by the ovaries is reduced. The drop-in blood-estrogen levels triggers common symptoms of menopause e.g. hot ?ashes; insomnia; heavy sweating (especially at night, which further contributes to insomnia); headaches; mood swings, and depression. Extracts of Black Cohosh (Cimicifuga racemosa) extract standardized to contain speci?c amount of triterpene glycosides (e.g. deoxyactein), that provide selective estrogen receptor modulation, serotonergic action, antioxidant and in?ammatory e?ects. Soy (Glycine max L.) standardized extract complex contains genistein, daidzein, and glycitein which are iso?avones – phytoestrogens that bind with the estrogen receptor (ER) beta, similar to the natural estrogen, increase in the women's serum levels of sex hormone-binding globulin (SHBG), decrease the amount of free testosterone and free estradiol and thereby lower the steroids biological activity, inhibit tyrosine kinase preventing osteoclasts domination in bone tissue, reduce LDL cholesterol and a signi?cant increase HDL cholesterol level, and on these way ?avonoids may control menopause symptoms, prevent osteoporosis and atherosclerosis development. Lin (?ax) seed (Linum usitatissimum) standardized extract content high quantities of “dietary lignan - one of the three major classes of phytoestrogen” and the most important lignan present is secoisolariciresinol diglucoside (SDG). Lignans seem to reduce the excess testosterone and follicle stimulating hormone (FSH) levels which play a key role in many hormone dependent diseases. Due to this properties ?ax extract impacts severity and frequency of hot ?ashes, night sweating, vaginal atrophy, and decrease in endometrial thickness. Horny goat weed (Epimedium) extract contains icariin -  a ?avonoid glycoside that osteocalcin expression, and can inhibit osteoclastic activity of bone as well as stimulate osteoblast activity. In clinical use icariin demonstrated capability increase bone density in postmenopausal women. Extract from St. John's Wort (Hypericum perforatum) prevents depression and mood disorder development. Some data suggest that hypericin is the active ingredient and other evidence suggests that hyperforin is the active ingredient of Hypericum perforatum. Hypericum extract may interfere with presynaptic serotonin uptake and reversible 50% decrease in the rate of serotonin transport improving the condition of patient with depression. Hypericin may also a?ect activity at GABA receptor level. Other proposed mechanisms are interleukin-6 inhibition, beta-adrenoceptor down- regulation and increase in levels of endorphins or melatonin. 


• In complex relief of symptoms during pre- and post-menopause such as breast pain and breast tenderness, night sweats and hot ?ashes, headache, anxiety, irritability, mood swings, depression, sleep disturbance and mood disorder development;

• In complex prophylaxis of osteoporosis and atherosclerosis in pre- and post-menopause women;

• In complex management of disorders related to sexual hormones in women;