Grand Medical Group

About us

Grand Medical Group AG is a group of pharmaceutical companies specialized in the development, production, registration and introduction into medical practice of modern innovative products based on organic, synthetic and herbal compounds.

read more

10 Kornmarkt Street, CH - 6004 Luzern, Switzerland

+41 415880810


Each ml of solution for injection contains 2 mg thiocholchiside, ?30


ATC code: MO3BX03, Muscle relaxant Thiocolchicoside is a semi-synthetic sulphurated derivative of colchicoside, with myorelaxant pharmacological activity. Thiocolchicoside acting as a GABA-A receptor antagonist, its myorelaxant e?ects could be exerted at the supraspinal level, via complex regulatory mechanism, although a glycinergic mechanism of action cannot be excluded. Thiocolchicoside was also found to posses anti-in?ammatory and analgesic activities in a variety of experimental models after oral, subcutaneous, intraperitoneal and intramuscular administration. Moreover, in pharmaco-EEG studies, thiocholchiside and its main metabolite were shown to be devoid of any sedative e?ect.


KEPLERON is indicated for symptomatic treatment of the painful muscular spasm in simple how low back pain.